Chronic Myeloid Leukemia with an e6a2 BCR-ABL1 Fusion Transcript: Cooperating Mutations at Blast Crisis and Molecular Monitoring

A minority of chronic myeloid leukemia patients (CML) express a variety of atypical BCR-ABL1 fusion variants and, of these, the e6a2 BCR-ABL1 fusion is generally associated with an aggressive disease course. Progression of CML to blast crisis is associated with acquisition of additional somatic muta...

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Detalles Bibliográficos
Autores principales: Crampe, Mireille, Haslam, Karl, Groarke, Emma, Kelleher, Eileen, O'Shea, Derville, Conneally, Eibhlin, Langabeer, Stephen E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5662812/
https://www.ncbi.nlm.nih.gov/pubmed/29123930
http://dx.doi.org/10.1155/2017/9071702

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5662812/
https://www.ncbi.nlm.nih.gov/pubmed/29123930
http://dx.doi.org/10.1155/2017/9071702

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