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Membrane dynamics and organelle biogenesis—lipid pipelines and vesicular carriers
Discoveries spanning several decades have pointed to vital membrane lipid trafficking pathways involving both vesicular and non-vesicular carriers. But the relative contributions for distinct membrane delivery pathways in cell growth and organelle biogenesis continue to be a puzzle. This is because...
| Autores principales: | , , , , , , , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663033/ https://www.ncbi.nlm.nih.gov/pubmed/29089042 http://dx.doi.org/10.1186/s12915-017-0432-0 |
| _version_ | 1783274749237919744 |
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| author | Stefan, Christopher J. Trimble, William S. Grinstein, Sergio Drin, Guillaume Reinisch, Karin De Camilli, Pietro Cohen, Sarah Valm, Alex M. Lippincott-Schwartz, Jennifer Levine, Tim P. Iaea, David B. Maxfield, Frederick R. Futter, Clare E. Eden, Emily R. Judith, Delphine van Vliet, Alexander R. Agostinis, Patrizia Tooze, Sharon A. Sugiura, Ayumu McBride, Heidi M. |
| author_facet | Stefan, Christopher J. Trimble, William S. Grinstein, Sergio Drin, Guillaume Reinisch, Karin De Camilli, Pietro Cohen, Sarah Valm, Alex M. Lippincott-Schwartz, Jennifer Levine, Tim P. Iaea, David B. Maxfield, Frederick R. Futter, Clare E. Eden, Emily R. Judith, Delphine van Vliet, Alexander R. Agostinis, Patrizia Tooze, Sharon A. Sugiura, Ayumu McBride, Heidi M. |
| author_sort | Stefan, Christopher J. |
| collection | PubMed |
| description | Discoveries spanning several decades have pointed to vital membrane lipid trafficking pathways involving both vesicular and non-vesicular carriers. But the relative contributions for distinct membrane delivery pathways in cell growth and organelle biogenesis continue to be a puzzle. This is because lipids flow from many sources and across many paths via transport vesicles, non-vesicular transfer proteins, and dynamic interactions between organelles at membrane contact sites. This forum presents our latest understanding, appreciation, and queries regarding the lipid transport mechanisms necessary to drive membrane expansion during organelle biogenesis and cell growth. |
| format | Online Article Text |
| id | pubmed-5663033 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2017 |
| publisher | BioMed Central |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-56630332017-11-01 Membrane dynamics and organelle biogenesis—lipid pipelines and vesicular carriers Stefan, Christopher J. Trimble, William S. Grinstein, Sergio Drin, Guillaume Reinisch, Karin De Camilli, Pietro Cohen, Sarah Valm, Alex M. Lippincott-Schwartz, Jennifer Levine, Tim P. Iaea, David B. Maxfield, Frederick R. Futter, Clare E. Eden, Emily R. Judith, Delphine van Vliet, Alexander R. Agostinis, Patrizia Tooze, Sharon A. Sugiura, Ayumu McBride, Heidi M. BMC Biol Forum Discoveries spanning several decades have pointed to vital membrane lipid trafficking pathways involving both vesicular and non-vesicular carriers. But the relative contributions for distinct membrane delivery pathways in cell growth and organelle biogenesis continue to be a puzzle. This is because lipids flow from many sources and across many paths via transport vesicles, non-vesicular transfer proteins, and dynamic interactions between organelles at membrane contact sites. This forum presents our latest understanding, appreciation, and queries regarding the lipid transport mechanisms necessary to drive membrane expansion during organelle biogenesis and cell growth. BioMed Central 2017-10-31 /pmc/articles/PMC5663033/ /pubmed/29089042 http://dx.doi.org/10.1186/s12915-017-0432-0 Text en © Stefan et al. 2017 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
| spellingShingle | Forum Stefan, Christopher J. Trimble, William S. Grinstein, Sergio Drin, Guillaume Reinisch, Karin De Camilli, Pietro Cohen, Sarah Valm, Alex M. Lippincott-Schwartz, Jennifer Levine, Tim P. Iaea, David B. Maxfield, Frederick R. Futter, Clare E. Eden, Emily R. Judith, Delphine van Vliet, Alexander R. Agostinis, Patrizia Tooze, Sharon A. Sugiura, Ayumu McBride, Heidi M. Membrane dynamics and organelle biogenesis—lipid pipelines and vesicular carriers |
| title | Membrane dynamics and organelle biogenesis—lipid pipelines and vesicular carriers |
| title_full | Membrane dynamics and organelle biogenesis—lipid pipelines and vesicular carriers |
| title_fullStr | Membrane dynamics and organelle biogenesis—lipid pipelines and vesicular carriers |
| title_full_unstemmed | Membrane dynamics and organelle biogenesis—lipid pipelines and vesicular carriers |
| title_short | Membrane dynamics and organelle biogenesis—lipid pipelines and vesicular carriers |
| title_sort | membrane dynamics and organelle biogenesis—lipid pipelines and vesicular carriers |
| topic | Forum |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663033/ https://www.ncbi.nlm.nih.gov/pubmed/29089042 http://dx.doi.org/10.1186/s12915-017-0432-0 |
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