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Comparative epigenomics in the Brassicaceae reveals two evolutionarily conserved modes of PRC2-mediated gene regulation

BACKGROUND: Polycomb Repressive Complexes 2 (PRC2) are multi-protein chromatin modifiers that are evolutionarily conserved among eukaryotes and play key roles in the regulation of gene expression, notably through the trimethylation of lysine 27 of histone H3 (H3K27me3). Although PRC2-mediated gene r...

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Detalles Bibliográficos
Autores principales: Chica, Claudia, Louis, Alexandra, Roest Crollius, Hugues, Colot, Vincent, Roudier, François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663038/
https://www.ncbi.nlm.nih.gov/pubmed/29084582
http://dx.doi.org/10.1186/s13059-017-1333-9