Characterizing temporal genomic heterogeneity in pediatric high-grade gliomas

Pediatric high-grade gliomas (pHGGs) are aggressive neoplasms representing approximately 20% of brain tumors in children. Current therapies offer limited disease control, and patients have a poor prognosis. Empiric use of targeted therapy, especially at progression, is increasingly practiced despite...

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Detalles Bibliográficos
Autores principales: Salloum, Ralph, McConechy, Melissa K., Mikael, Leonie G., Fuller, Christine, Drissi, Rachid, DeWire, Mariko, Nikbakht, Hamid, De Jay, Nicolas, Yang, Xiaodan, Boue, Daniel, Chow, Lionel M. L., Finlay, Jonathan L., Gayden, Tenzin, Karamchandani, Jason, Hummel, Trent R., Olshefski, Randal, Osorio, Diana S., Stevenson, Charles, Kleinman, Claudia L., Majewski, Jacek, Fouladi, Maryam, Jabado, Nada
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663045/
https://www.ncbi.nlm.nih.gov/pubmed/29084603
http://dx.doi.org/10.1186/s40478-017-0479-8

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