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Clinical and genetic characterization of hereditary breast cancer in a Chinese population

BACKGROUND: Breast cancer develops as a result of multiple gene mutations in combination with environmental risk factors. Causative variants in genes such as BRCA1 and/or BRCA2 have been shown to account for hereditary nature of certain breast cancers. However,other genes, such as ATM, PALB2, BRIP1,...

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Detalles Bibliográficos
Autores principales: Jian, Wenjing, Shao, Kang, Qin, Qi, Wang, Xiaohong, Song, Shufen, Wang, Xianming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663067/
https://www.ncbi.nlm.nih.gov/pubmed/29093764
http://dx.doi.org/10.1186/s13053-017-0079-4