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Role of AP-2α and MAPK7 in the regulation of autocrine TGF-β/miR-200b signals to maintain epithelial-mesenchymal transition in cholangiocarcinoma

BACKGROUND: Cholangiocarcinoma (CCA) is characterized by early lymphatic, metastasis, and low survival rate. Epithelial-mesenchymal transition (EMT) is able to induce tumor metastasis. Although the TGF-β/miR-200 signals promote EMT in various types of cancer, the regulatory mechanism in CCA is still...

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Detalles Bibliográficos
Autores principales:	Zhang, Dawei, Li, Haiyan, Jiang, Xiaofeng, Cao, Liangqi, Wen, Zilong, Yang, Xuewei, Xue, Ping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663068/ https://www.ncbi.nlm.nih.gov/pubmed/29084594 http://dx.doi.org/10.1186/s13045-017-0528-6

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