H2A O-GlcNAcylation at serine 40 functions genomic protection in association with acetylated H2AZ or γH2AX

BACKGROUND: We have previously reported a novel O-GlcNAc modification at serine 40 (S40) of H2A (H2AS40Gc). S40-type H2A isoforms susceptible to O-GlcNAcylation are evolutionarily new and restricted to the viviparous animals; however, the biological function of H2AS40Gc is largely unknown. H2A isofo...

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Detalles Bibliográficos
Autores principales: Hayakawa, Koji, Hirosawa, Mitsuko, Tani, Ruiko, Yoneda, Chikako, Tanaka, Satoshi, Shiota, Kunio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663087/
https://www.ncbi.nlm.nih.gov/pubmed/29084613
http://dx.doi.org/10.1186/s13072-017-0157-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663087/
https://www.ncbi.nlm.nih.gov/pubmed/29084613
http://dx.doi.org/10.1186/s13072-017-0157-x

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