Synthetic regulatory RNAs selectively suppress the progression of bladder cancer

The traditional treatment for cancer is lack of specificity and efficacy. Modular synthetic regulatory RNAs, such as inhibitive RNA (iRNA) and active RNA (aRNA), may overcome these limitations. Here, we synthesize a new iRNA to bind the upstream activating sequence (UAS) of a minimal promoter that d...

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Detalles Bibliográficos
Autores principales: Zhuang, Chengle, Huang, Xinbo, Zhuang, Changshui, Luo, Xiaomin, Zhang, Xiaowei, Cai, Zhiming, Gui, Yaoting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663129/
https://www.ncbi.nlm.nih.gov/pubmed/29084575
http://dx.doi.org/10.1186/s13046-017-0626-x

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