Combination of EZH2 inhibitor and BET inhibitor for treatment of diffuse intrinsic pontine glioma

BACKGROUND: Diffuse intrinsic pontine glioma is an infiltrative, often high-grade glioma of the brainstem that is not amenable to surgical resection. The current treatment of DIPG by radiation therapy showed dramatically improvement of patient’s condition, however, the tumor recurs rapidly. More and...

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Detalles Bibliográficos
Autores principales: Zhang, Yaqin, Dong, Weijie, Zhu, Junying, Wang, Lizhu, Wu, Xinjian, Shan, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663148/
https://www.ncbi.nlm.nih.gov/pubmed/29118968
http://dx.doi.org/10.1186/s13578-017-0184-0

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