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Safety and efficacy of intra-arterial hepatic chemotherapy with doxorubicin-loaded nanoparticles in hepatocellular carcinoma

BACKGROUND: Doxorubicin Transdrug (DT), a nanoformulation of doxorubicin, was demonstrated to overcome the chemoresistance of hepatocellular carcinoma (HCC) in preclinical models. Its efficacy and safety were thus investigated in phase I and randomised phase II trials in unresectable HCC. PATIENTS A...

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Detalles Bibliográficos
Autores principales:	Merle, Philippe, Camus, Philippe, Abergel, Armand, Pageaux, Georges Philippe, Masliah, Claude, Bronowicki, Jean Pierre, Zarski, Jean Pierre, Pelletier, Gilles, Bouattour, Mohamed, Farloux, Laetitia, Dorval, Etienne, verset, Gilles, Si-Ahmed, Si-Nafa, Doffoel, Michel, Couzigou, Patrice, Taieb, Julien, Vasseur, Bérangère, Attali, Pierre
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2017
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663255/ https://www.ncbi.nlm.nih.gov/pubmed/29104762 http://dx.doi.org/10.1136/esmoopen-2017-000238

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