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Long and short of optimal stent design

The ideal stent must fulfil a broad range of technical requirements. Stents must be securely crimped onto the delivery balloon and, in this form, must have a low profile and be sufficiently flexible to facilitate deliverability to the lesion site without distortion or displacement. Following expansi...

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Autores principales: Watson, Timothy, Webster, Mark W I, Ormiston, John A, Ruygrok, Peter N, Stewart, James T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663262/
https://www.ncbi.nlm.nih.gov/pubmed/29118997
http://dx.doi.org/10.1136/openhrt-2017-000680
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author Watson, Timothy
Webster, Mark W I
Ormiston, John A
Ruygrok, Peter N
Stewart, James T
author_facet Watson, Timothy
Webster, Mark W I
Ormiston, John A
Ruygrok, Peter N
Stewart, James T
author_sort Watson, Timothy
collection PubMed
description The ideal stent must fulfil a broad range of technical requirements. Stents must be securely crimped onto the delivery balloon and, in this form, must have a low profile and be sufficiently flexible to facilitate deliverability to the lesion site without distortion or displacement. Following expansion, stents must exert sufficient radial force on the vessel wall to overcome lesion resistance and elastic recoil. To achieve an optimal lumen diameter, the lesion must be uniformly and adequately scaffolded, with minimal tissue prolapse between struts but without compromising side-branch access. Furthermore, the deployed stent must conform to the vessel curvature to minimise vessel distortion, particularly at the stent edges. Radio-opacity is also important to guide safe positioning, adequate deployment and postdilataion and to permit assessment of optimal stent expansion. Equally though, the stent lumen must also be sufficiently visible to allow radiographic assessment of flow dynamics and restenosis. Efforts to optimise one characteristic of stent design may have detrimental effects on another. Thus, currently available stents all reflect a compromise between competing desirable features and have subtle differences in their performance characteristics. Striving to achieve stents with optimal deliverability, conformability and radial strength led to a reduction in longitudinal strength. The importance of this parameter was highlighted by complications occurring in the real-world setting where percutaneous coronary intervention is often undertaken in challenging anatomy. This review focuses on aspects of stent design relevant to longitudinal strength.
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spelling pubmed-56632622017-11-08 Long and short of optimal stent design Watson, Timothy Webster, Mark W I Ormiston, John A Ruygrok, Peter N Stewart, James T Open Heart Review The ideal stent must fulfil a broad range of technical requirements. Stents must be securely crimped onto the delivery balloon and, in this form, must have a low profile and be sufficiently flexible to facilitate deliverability to the lesion site without distortion or displacement. Following expansion, stents must exert sufficient radial force on the vessel wall to overcome lesion resistance and elastic recoil. To achieve an optimal lumen diameter, the lesion must be uniformly and adequately scaffolded, with minimal tissue prolapse between struts but without compromising side-branch access. Furthermore, the deployed stent must conform to the vessel curvature to minimise vessel distortion, particularly at the stent edges. Radio-opacity is also important to guide safe positioning, adequate deployment and postdilataion and to permit assessment of optimal stent expansion. Equally though, the stent lumen must also be sufficiently visible to allow radiographic assessment of flow dynamics and restenosis. Efforts to optimise one characteristic of stent design may have detrimental effects on another. Thus, currently available stents all reflect a compromise between competing desirable features and have subtle differences in their performance characteristics. Striving to achieve stents with optimal deliverability, conformability and radial strength led to a reduction in longitudinal strength. The importance of this parameter was highlighted by complications occurring in the real-world setting where percutaneous coronary intervention is often undertaken in challenging anatomy. This review focuses on aspects of stent design relevant to longitudinal strength. BMJ Publishing Group 2017-10-30 /pmc/articles/PMC5663262/ /pubmed/29118997 http://dx.doi.org/10.1136/openhrt-2017-000680 Text en © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted. This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
spellingShingle Review
Watson, Timothy
Webster, Mark W I
Ormiston, John A
Ruygrok, Peter N
Stewart, James T
Long and short of optimal stent design
title Long and short of optimal stent design
title_full Long and short of optimal stent design
title_fullStr Long and short of optimal stent design
title_full_unstemmed Long and short of optimal stent design
title_short Long and short of optimal stent design
title_sort long and short of optimal stent design
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663262/
https://www.ncbi.nlm.nih.gov/pubmed/29118997
http://dx.doi.org/10.1136/openhrt-2017-000680
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