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Hdac3 regulates lymphovenous and lymphatic valve formation
Lymphedema, the most common lymphatic anomaly, involves defective lymphatic valve development; yet the epigenetic modifiers underlying lymphatic valve morphogenesis remain elusive. Here, we showed that during mouse development, the histone-modifying enzyme histone deacetylase 3 (Hdac3) regulates the...
Autores principales: | Janardhan, Harish P., Milstone, Zachary J., Shin, Masahiro, Lawson, Nathan D., Keaney, John F., Trivedi, Chinmay M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663362/ https://www.ncbi.nlm.nih.gov/pubmed/29035278 http://dx.doi.org/10.1172/JCI92852 |
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