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Post-weaning epiphysiolysis causes distal femur dysplasia and foreshortened hindlimbs in fetuin-A-deficient mice

Fetuin-A / α(2)-Heremans-Schmid-glycoprotein (gene name Ahsg) is a systemic inhibitor of ectopic calcification. Due to its high affinity for calcium phosphate, fetuin-A is highly abundant in mineralized bone matrix. Foreshortened femora in fetuin-A-deficient Ahsg(-/-) mice indicated a role for fetui...

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Detalles Bibliográficos
Autores principales: Brylka, Laura J., Köppert, Sina, Babler, Anne, Kratz, Beate, Denecke, Bernd, Yorgan, Timur A., Etich, Julia, Costa, Ivan G., Brachvogel, Bent, Boor, Peter, Schinke, Thorsten, Jahnen-Dechent, Willi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663435/
https://www.ncbi.nlm.nih.gov/pubmed/29088242
http://dx.doi.org/10.1371/journal.pone.0187030