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Half of rifampicin-resistant Mycobacterium tuberculosis complex isolated from tuberculosis patients in Sub-Saharan Africa have concomitant resistance to pyrazinamide
BACKGROUND: Besides inclusion in 1(st) line regimens against tuberculosis (TB), pyrazinamide (PZA) is used in 2(nd) line anti-TB regimens, including in the short regimen for multidrug-resistant TB (MDR-TB) patients. Guidelines and expert opinions are contradictory about inclusion of PZA in case of r...
Autores principales: | , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663438/ https://www.ncbi.nlm.nih.gov/pubmed/29088294 http://dx.doi.org/10.1371/journal.pone.0187211 |