Half of rifampicin-resistant Mycobacterium tuberculosis complex isolated from tuberculosis patients in Sub-Saharan Africa have concomitant resistance to pyrazinamide

BACKGROUND: Besides inclusion in 1(st) line regimens against tuberculosis (TB), pyrazinamide (PZA) is used in 2(nd) line anti-TB regimens, including in the short regimen for multidrug-resistant TB (MDR-TB) patients. Guidelines and expert opinions are contradictory about inclusion of PZA in case of r...

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Detalles Bibliográficos
Autores principales: Ngabonziza, Jean Claude Semuto, Diallo, Awa Ba, Tagliani, Elisa, Diarra, Bassirou, Kadanga, Abalo Essosimna, Togo, Antieme Combo George, Thiam, Aliou, de Rijk, Willem Bram, Alagna, Riccardo, Houeto, Sabine, Ba, Fatoumata, Dagnra, Anoumou Yaotsè, Ivan, Emil, Affolabi, Dissou, Schwoebel, Valérie, Trebucq, Arnaud, de Jong, Bouke Catherine, Rigouts, Leen, Daneau, Géraldine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663438/
https://www.ncbi.nlm.nih.gov/pubmed/29088294
http://dx.doi.org/10.1371/journal.pone.0187211

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