Questioning the role of selected somatic PIK3C2B mutations in squamous non-small cell lung cancer oncogenesis

PI3K signaling is frequently dysregulated in NSCLC-SQCC. In contrast to well characterized components of the PI3K signaling network contributing to the formation of SQCC, potential oncogenic effects of alterations in PIK3C2B are poorly understood. Here, a large cohort (n = 362) of NSCLC-SQCC was sel...

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Detalles Bibliográficos
Autores principales: Kind, Marcus, Klukowska-Rötzler, Jolanta, Berezowska, Sabina, Arcaro, Alexandre, Charles, Roch-Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663493/
https://www.ncbi.nlm.nih.gov/pubmed/29088297
http://dx.doi.org/10.1371/journal.pone.0187308

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663493/
https://www.ncbi.nlm.nih.gov/pubmed/29088297
http://dx.doi.org/10.1371/journal.pone.0187308

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