Cargando…

Questioning the role of selected somatic PIK3C2B mutations in squamous non-small cell lung cancer oncogenesis

PI3K signaling is frequently dysregulated in NSCLC-SQCC. In contrast to well characterized components of the PI3K signaling network contributing to the formation of SQCC, potential oncogenic effects of alterations in PIK3C2B are poorly understood. Here, a large cohort (n = 362) of NSCLC-SQCC was sel...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kind, Marcus, Klukowska-Rötzler, Jolanta, Berezowska, Sabina, Arcaro, Alexandre, Charles, Roch-Philippe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663493/ https://www.ncbi.nlm.nih.gov/pubmed/29088297 http://dx.doi.org/10.1371/journal.pone.0187308

Ejemplares similares

Injury patterns of non-fatal accidents related to ice hockey, an analysis of 7 years of admission to a Level-1 Emergency Centre in Switzerland
por: Gilardi, Viola, et al.
Publicado: (2023)

Somatic Mutations of PIK3R1 Promote Gliomagenesis
por: Quayle, Steven N., et al.
Publicado: (2012)

Characterization of PIK3CA and PIK3R1 somatic mutations in Chinese breast cancer patients
por: Chen, Li, et al.
Publicado: (2018)

Somatic gain-of-function mutations in PIK3CA in patients with macrodactyly
por: Rios, Jonathan J., et al.
Publicado: (2013)

Frequency and spectrum of PIK3CA somatic mutations in breast cancer
por: Martínez-Sáez, Olga, et al.
Publicado: (2020)

Functional characterization of a novel somatic oncogenic mutation of PIK3CB
por: Whale, Andrew D, et al.
Publicado: (2017)

Somatic activating mutations in PIK3CA cause generalized lymphatic anomaly
por: Rodriguez-Laguna, Lara, et al.
Publicado: (2019)

Somatic mutation in PIK3CA is a late event in cervical carcinogenesis
por: Verlaat, Wina, et al.
Publicado: (2015)

c-Myc activation promotes cofilin-mediated F-actin cytoskeleton remodeling and telomere homeostasis as a response to oxidant-based DNA damage in medulloblastoma cells
por: Lewinska, Anna, et al.
Publicado: (2019)

Temporomandibular joint dislocation: a retrospective study from a Swiss urban emergency department
por: Papoutsis, Giorgos, et al.
Publicado: (2018)

Repatriations of Ill and Injured Travelers and Emigrants to Switzerland: A Retrospective Analysis at a Tertiary Emergency Department from 2013–2018
por: Brockhus, Lara, et al.
Publicado: (2021)

Health Status of Afghan Refugees in Europe: Policy and Practice Implications for an Optimised Healthcare
por: Matsangos, Michael, et al.
Publicado: (2022)

Floorball Injuries Presenting to a Swiss Adult Emergency Department: A Retrospective Study (2013–2019)
por: Radtke, Stephanie, et al.
Publicado: (2021)

Somatic mutation and gain of copy number of PIK3CA in human breast cancer
por: Wu, Guojun, et al.
Publicado: (2005)

Trampolining Accidents in an Adult Emergency Department: Analysis of Trampolining Evolution Regarding Severity and Occurrence of Injuries
por: Sasse, Nora, et al.
Publicado: (2022)

Who Let the Dogs Out? Unmasking the Neglected: A Semi-Systematic Review on the Enduring Impact of Toxocariasis, a Prevalent Zoonotic Infection
por: Henke, Katrin, et al.
Publicado: (2023)

Clinical Presentations of Adolescents Aged 16–18 Years in the Adult Emergency Department
por: Brockhus, Lara Aurora, et al.
Publicado: (2021)

Presentations to the Emergency Department for Problems Related to Mental Health: Sex Differences in Adolescents
por: Flury, Raffaela M., et al.
Publicado: (2022)

Sex differences in sledging injuries: a retrospective 10-season study from a Swiss level 1 trauma centre
por: Klukowska-Rötzler, Jolanta, et al.
Publicado: (2023)

Germline ATM mutation and somatic PIK3CA and BCOR mutations found in an infant with aggressive orbital embryonal rhabdomyosarcoma
por: Jaru-ampornpan, Pimkwan, et al.
Publicado: (2021)

Severity and pattern of injuries caused by Swiss wrestling (Schwingen): first retrospective study at a level I University Emergency Department in Switzerland
por: Maliachovas, Nikolaos K, et al.
Publicado: (2018)

Trends and Weekly Cycles in a Large Swiss Emergency Centre: A 10 Year Period at the University Hospital of Bern
por: Braun, Christian T., et al.
Publicado: (2017)

Presentations Related to Acute Paracetamol Intoxication in an Urban Emergency Department in Switzerland
por: Piotrowska, Natalia, et al.
Publicado: (2019)

A girl with CLOVES syndrome with a recurrent PIK3CA somatic mutation and pancreatic steatosis
por: Hanafusa, Hiroaki, et al.
Publicado: (2019)

A somatic mutation in PIK3CD unravels a novel candidate gene for lymphatic malformation
por: Wang, Shengcai, et al.
Publicado: (2021)

Case Report of Fibro-Adipose Vascular Anomaly (FAVA) with Activating Somatic PIK3CA Mutation
por: Driskill, Jordan H., et al.
Publicado: (2022)

Case report: PIK3CA somatic mutation leading to Klippel Trenaunay Syndrome and multiple tumors
por: Serio, Viola Bianca, et al.
Publicado: (2023)

Injuries in outdoor climbing: a retrospective single-centre cohort study at a level 1 emergency department in Switzerland
por: Krieger, Chantal Selina, et al.
Publicado: (2022)

Work-Related Injuries among Insured Construction Workers Presenting to a Swiss Adult Emergency Department: A Retrospective Study (2016–2020)
por: Dethlefsen, Ralf, et al.
Publicado: (2022)

BRAF and PIK3CA genes are somatically mutated in hepatocellular carcinoma among patients from South Italy
por: Colombino, M, et al.
Publicado: (2012)

Improved survival associated with somatic PIK3CA mutations in copy-number low endometrioid endometrial adenocarcinoma
por: LIN, DOUGLAS I.
Publicado: (2015)

Evaluation of Circulating Tumor DNA in Patients with Ovarian Cancer Harboring Somatic PIK3CA or KRAS Mutations
por: Ogasawara, Aiko, et al.
Publicado: (2020)

Early activating somatic PIK3CA mutations promote ectopic muscle development and upper limb overgrowth
por: Frisk, Sofia, et al.
Publicado: (2019)

Correction to: A somatic mutation in PIK3CD unravels a novel candidate gene for lymphatic malformation
por: Wang, Shengcai, et al.
Publicado: (2021)

PIK3CA gene mutations in Northwest Chinese esophageal squamous cell carcinoma
por: Liu, Shi-Yuan, et al.
Publicado: (2017)

RAS Mutations and Oncogenesis: Not all RAS Mutations are Created Equally
por: Miller, Mark Steven, et al.
Publicado: (2012)

Trauma Characteristics Associated with E-Scooter Accidents in Switzerland—A Case Series Study
por: Bracher, Ava Insa, et al.
Publicado: (2023)

PIK3CA-mutations in breast cancer
por: Reinhardt, Kristin, et al.
Publicado: (2022)

Somatic non-cancerous PIK3CA-related overgrowth syndrome treated with alpelisib in North America
por: Garneau, Alexandre P., et al.
Publicado: (2021)

Acquired somatic TP53 or PIK3CA mutations are potential predictors of when polyps evolve into colorectal cancer
por: Chang, Pi-Yueh, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_g9h2dj5p4jjc5e05kddtt0dh1v