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AKR7A3 suppresses tumorigenicity and chemoresistance in hepatocellular carcinoma through attenuation of ERK, c-Jun and NF-κB signaling pathways

Hepatocellular carcinoma (HCC), which accounts for 85–90% of primary liver cancer, is now the second leading cause of cancer-related mortality worldwide. Here we reported that Aldo-Keto Reductase family 7A isoform 3 (AKR7A3) is frequently down-regulated in HCC, associating with poor overall survival...

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Detalles Bibliográficos
Autores principales:	Chow, Raymond Kwok Kei, Tsz-Kwan Sin, Sarah, Liu, Ming, Li, Yan, Man Chan, Tim Hon, Song, Yangyang, Chen, Leilei, Lai-Wan Kwong, Dora, Guan, Xin-Yuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663529/ https://www.ncbi.nlm.nih.gov/pubmed/29137357 http://dx.doi.org/10.18632/oncotarget.12726

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