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Targeting Src attenuates peritoneal fibrosis and inhibits the epithelial to mesenchymal transition

Src has been reported to mediate tissue fibrosis in several organs, but its role in peritoneal fibrosis remains unknown. In this study, we evaluated the therapeutic effect of KX2-391, a highly selective inhibitor of Src, on the development of peritoneal fibrosis in a rat model. Daily intraperitoneal...

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Detalles Bibliográficos
Autores principales:	Wang, Jun, Wang, Li, Xu, Liuqing, Shi, Yingfeng, Liu, Feng, Qi, Hualin, Liu, Na, Zhuang, Shougang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663561/ https://www.ncbi.nlm.nih.gov/pubmed/29137389 http://dx.doi.org/10.18632/oncotarget.20040

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