TGFBR-IDH1-Cav1 axis promotes TGF-β signalling in cancer-associated fibroblast

TGF-β signalling plays an important role in fibroblasts activation and tumour progression. Here, we report that the TGFBR-IDH1-Cav1 axis promotes TGF- β signalling in fibroblasts. Our data demonstrated that IDH1 was downregulated by TGF-β signalling in fibroblasts, and downregulation of IDH1 increas...

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Detalles Bibliográficos
Autores principales: Hou, Xiaodan, Zhang, Jieying, Wang, Yongbin, Xiong, Wujun, Mi, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663568/
https://www.ncbi.nlm.nih.gov/pubmed/29137396
http://dx.doi.org/10.18632/oncotarget.20861

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663568/
https://www.ncbi.nlm.nih.gov/pubmed/29137396
http://dx.doi.org/10.18632/oncotarget.20861

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