Downregulation of the Sonic Hedgehog/Gli pathway transcriptional target Neogenin-1 is associated with basal cell carcinoma aggressiveness

Basal Cell Carcinoma (BCC) is one of the most diagnosed cancers worldwide. It develops due to an unrestrained Sonic Hedgehog (SHH) signaling activity in basal cells of the skin. Certain subtypes of BCC are more aggressive than others, although the molecular basis of this phenomenon remains unknown....

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Detalles Bibliográficos
Autores principales: Casas, Bárbara S., Adolphe, Christelle, Lois, Pablo, Navarrete, Nelson, Solís, Natalia, Bustamante, Eva, Gac, Patricio, Cabané, Patricio, Gallegos, Ivan, Wainwright, Brandon J., Palma, Verónica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663572/
https://www.ncbi.nlm.nih.gov/pubmed/29137400
http://dx.doi.org/10.18632/oncotarget.21061

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