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Long non-coding RNA SNHG15 inhibits P15 and KLF2 expression to promote pancreatic cancer proliferation through EZH2-mediated H3K27me3

Long non-coding RNA (lncRNA) is emerging as an critical regulator in multiple cancers, including pancreatic cancer (PC). Recently, lncRNA SNHG15 was found to be up-regulated in gastric cancer and hepatocellular carcinoma, exerting oncogenic effects. Nevertheless, the biological function and regulato...

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Detalles Bibliográficos
Autores principales: Ma, Zhonghua, Huang, Hesuyuan, Wang, Jirong, Zhou, Yan, Pu, Fuxing, Zhao, Qinghong, Peng, Peng, Hui, Bingqing, Ji, Hao, Wang, Keming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663584/
https://www.ncbi.nlm.nih.gov/pubmed/29137412
http://dx.doi.org/10.18632/oncotarget.20359