PTEN loss is associated with prostate cancer recurrence and alterations in tumor DNA methylation profiles

BACKGROUND: Prostate cancer (PCa) with loss of the tumor suppressor gene PTEN has an unfavorable prognosis. DNA methylation profiles associated with PTEN loss may provide further insights into the mechanisms underlying these more aggressive, clinically relevant tumors. METHODS: The cohort included p...

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Detalles Bibliográficos
Autores principales: Geybels, Milan S., Fang, Min, Wright, Jonathan L., Qu, Xiaoyu, Bibikova, Marina, Klotzle, Brandy, Fan, Jian-Bing, Feng, Ziding, Ostrander, Elaine A., Nelson, Peter S., Stanford, Janet L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663600/
https://www.ncbi.nlm.nih.gov/pubmed/29137428
http://dx.doi.org/10.18632/oncotarget.20940

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663600/
https://www.ncbi.nlm.nih.gov/pubmed/29137428
http://dx.doi.org/10.18632/oncotarget.20940

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