DNA hypermethyation and silencing of PITX1 correlated with advanced stage and poor postoperative prognosis of esophageal squamous cell carcinoma

Esophageal squamous cell carcinoma (ESCC) is associated with the accumulation of genetic and epigenetic changes in the background mucosa. Dysregulated DNA methylation is known to lead to the inactivation of tumor suppressor genes and the activation of oncogenes. To identify the genes whose expressio...

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Detalles Bibliográficos
Autores principales: Otsubo, Takeshi, Yamada, Kazuhiko, Hagiwara, Teruki, Oshima, Kenshiro, Iida, Kei, Nishikata, Koro, Toyoda, Tetsuro, Igari, Toru, Nohara, Kyoko, Yamashita, Satoshi, Hattori, Masahira, Dohi, Taeko, Kawamura, Yuki I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663609/
https://www.ncbi.nlm.nih.gov/pubmed/29137437
http://dx.doi.org/10.18632/oncotarget.21375

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