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Indoleamine 2,3-Dioxygenase and Tolerance: Where Are We Now?

Cells expressing IDO suppress innate and adaptive immunity to promote tolerance by catabolizing the amino acid tryptophan (Trp) and other indole compounds. Interferon type I (IFN-I) and type II (IFN-II) produced at sites of inflammation or by activated immune cells are potent IDO inducers because ma...

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Detalles Bibliográficos
Autores principales:	Mellor, Andrew L., Lemos, Henrique, Huang, Lei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663846/ https://www.ncbi.nlm.nih.gov/pubmed/29163470 http://dx.doi.org/10.3389/fimmu.2017.01360

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