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Heparin at physiological concentration can enhance PEG-free in vitro infection with human hepatitis B virus

Hepatitis B virus (HBV) is a blood-borne pathogen responsible for chronic hepatitis, cirrhosis, and liver cancer. The mechanism of HBV entry into hepatocytes remains to be investigated. Recently, sodium taurocholate cotransporting polypeptide (NTCP) was discovered as a major HBV receptor based on an...

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Detalles Bibliográficos
Autores principales: Choijilsuren, Gansukh, Jhou, Ren-Shiang, Chou, Shu-Fan, Chang, Ching-Jen, Yang, Hwai-I, Chen, Yang-Yuan, Chuang, Wan-Long, Yu, Ming-Lung, Shih, Chiaho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663848/
https://www.ncbi.nlm.nih.gov/pubmed/29089529
http://dx.doi.org/10.1038/s41598-017-14573-9