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A histone-mimicking interdomain linker in a multidomain protein modulates multivalent histone binding

N-terminal histone tails are subject to many posttranslational modifications that are recognized by and interact with designated reader domains in histone-binding proteins. BROMO domain adjacent to zinc finger 2B (BAZ2B) is a multidomain histone-binding protein that contains two histone reader modul...

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Detalles Bibliográficos
Autores principales: Kostrhon, Sebastian, Kontaxis, Georg, Kaufmann, Tanja, Schirghuber, Erika, Kubicek, Stefan, Konrat, Robert, Slade, Dea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663869/
https://www.ncbi.nlm.nih.gov/pubmed/28864776
http://dx.doi.org/10.1074/jbc.M117.801464