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Shengjiang Xiexin Decoction Alters Pharmacokinetics of Irinotecan by Regulating Metabolic Enzymes and Transporters: A Multi-Target Therapy for Alleviating the Gastrointestinal Toxicity

Shengjiang Xiexin decoction (SXD), a classic traditional Chinese medical formula chronicled in Shang Han Lun, is used in modern clinical practice to decrease gastrointestinal toxicity induced by the chemotherapeutic drug irinotecan (CPT-11). In this study, the effect of SXD on the pharmacokinetics o...

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Detalles Bibliográficos
Autores principales:	Guan, Huan-yu, Li, Peng-fei, Wang, Xiao-ming, Yue, Jia-jing, He, Yang, Luo, Xiao-mei, Su, Mei-feng, Liao, Shang-gao, Shi, Yue
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663900/ https://www.ncbi.nlm.nih.gov/pubmed/29163158 http://dx.doi.org/10.3389/fphar.2017.00769

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