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Transcription instability in high‐risk neuroblastoma is associated with a global perturbation of chromatin domains
Chromosome instability has a pivotal role among the hallmarks of cancer, but its transcriptional counterpart is rarely considered a relevant factor in cell destabilization. To examine transcription instability (TIN), we first devised a metric we named TIN index and used it to evaluate TIN on a datas...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5664000/ https://www.ncbi.nlm.nih.gov/pubmed/28941026 http://dx.doi.org/10.1002/1878-0261.12139 |