β‐Catenin in desmoid‐type fibromatosis: deep insights into the role of T41A and S45F mutations on protein structure and gene expression

Desmoid‐type fibromatosis (DF) is a rare mesenchymal lesion with high risk of local recurrence. Specific β‐catenin mutations (S45F) appeared to be related to this higher risk compared to T41A‐mutated or wild‐type (WT). We explored the influence of both mutations and WT on structure stability and aff...

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Detalles Bibliográficos
Autores principales: Colombo, Chiara, Belfiore, Antonino, Paielli, Nicholas, De Cecco, Loris, Canevari, Silvana, Laurini, Erik, Fermeglia, Maurizio, Pricl, Sabrina, Verderio, Paolo, Bottelli, Stefano, Fiore, Marco, Stacchiotti, Silvia, Palassini, Elena, Gronchi, Alessandro, Pilotti, Silvana, Perrone, Federica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5664003/
https://www.ncbi.nlm.nih.gov/pubmed/28627792
http://dx.doi.org/10.1002/1878-0261.12101

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