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Curcumin: A Review of Its’ Effects on Human Health

Turmeric, a spice that has long been recognized for its medicinal properties, has received interest from both the medical/scientific world and from culinary enthusiasts, as it is the major source of the polyphenol curcumin. It aids in the management of oxidative and inflammatory conditions, metaboli...

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Autores principales: Hewlings, Susan J., Kalman, Douglas S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5664031/
https://www.ncbi.nlm.nih.gov/pubmed/29065496
http://dx.doi.org/10.3390/foods6100092
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author Hewlings, Susan J.
Kalman, Douglas S.
author_facet Hewlings, Susan J.
Kalman, Douglas S.
author_sort Hewlings, Susan J.
collection PubMed
description Turmeric, a spice that has long been recognized for its medicinal properties, has received interest from both the medical/scientific world and from culinary enthusiasts, as it is the major source of the polyphenol curcumin. It aids in the management of oxidative and inflammatory conditions, metabolic syndrome, arthritis, anxiety, and hyperlipidemia. It may also help in the management of exercise-induced inflammation and muscle soreness, thus enhancing recovery and performance in active people. In addition, a relatively low dose of the complex can provide health benefits for people that do not have diagnosed health conditions. Most of these benefits can be attributed to its antioxidant and anti-inflammatory effects. Ingesting curcumin by itself does not lead to the associated health benefits due to its poor bioavailability, which appears to be primarily due to poor absorption, rapid metabolism, and rapid elimination. There are several components that can increase bioavailability. For example, piperine is the major active component of black pepper and, when combined in a complex with curcumin, has been shown to increase bioavailability by 2000%. Curcumin combined with enhancing agents provides multiple health benefits. The purpose of this review is to provide a brief overview of the plethora of research regarding the health benefits of curcumin.
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spelling pubmed-56640312017-11-06 Curcumin: A Review of Its’ Effects on Human Health Hewlings, Susan J. Kalman, Douglas S. Foods Review Turmeric, a spice that has long been recognized for its medicinal properties, has received interest from both the medical/scientific world and from culinary enthusiasts, as it is the major source of the polyphenol curcumin. It aids in the management of oxidative and inflammatory conditions, metabolic syndrome, arthritis, anxiety, and hyperlipidemia. It may also help in the management of exercise-induced inflammation and muscle soreness, thus enhancing recovery and performance in active people. In addition, a relatively low dose of the complex can provide health benefits for people that do not have diagnosed health conditions. Most of these benefits can be attributed to its antioxidant and anti-inflammatory effects. Ingesting curcumin by itself does not lead to the associated health benefits due to its poor bioavailability, which appears to be primarily due to poor absorption, rapid metabolism, and rapid elimination. There are several components that can increase bioavailability. For example, piperine is the major active component of black pepper and, when combined in a complex with curcumin, has been shown to increase bioavailability by 2000%. Curcumin combined with enhancing agents provides multiple health benefits. The purpose of this review is to provide a brief overview of the plethora of research regarding the health benefits of curcumin. MDPI 2017-10-22 /pmc/articles/PMC5664031/ /pubmed/29065496 http://dx.doi.org/10.3390/foods6100092 Text en © 2017 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Hewlings, Susan J.
Kalman, Douglas S.
Curcumin: A Review of Its’ Effects on Human Health
title Curcumin: A Review of Its’ Effects on Human Health
title_full Curcumin: A Review of Its’ Effects on Human Health
title_fullStr Curcumin: A Review of Its’ Effects on Human Health
title_full_unstemmed Curcumin: A Review of Its’ Effects on Human Health
title_short Curcumin: A Review of Its’ Effects on Human Health
title_sort curcumin: a review of its’ effects on human health
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5664031/
https://www.ncbi.nlm.nih.gov/pubmed/29065496
http://dx.doi.org/10.3390/foods6100092
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