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Protein Misfolding and Aggregation as a Therapeutic Target for Polyglutamine Diseases
The polyglutamine (polyQ) diseases, such as Huntington’s disease and several types of spinocerebellar ataxias, are a group of inherited neurodegenerative diseases that are caused by an abnormal expansion of the polyQ tract in disease-causative proteins. Proteins with an abnormally expanded polyQ str...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5664055/ https://www.ncbi.nlm.nih.gov/pubmed/29019918 http://dx.doi.org/10.3390/brainsci7100128 |