Cargando…
The Emerging Role of Polo-Like Kinase 1 in Epithelial-Mesenchymal Transition and Tumor Metastasis
Polo-like kinase 1 (PLK1) is a serine/threonine kinase that plays a key role in the regulation of the cell cycle. PLK1 is overexpressed in a variety of human tumors, and its expression level often correlates with increased cellular proliferation and poor prognosis in cancer patients. It has been sug...
Autores principales: | Fu, Zheng, Wen, Donghua |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5664070/ https://www.ncbi.nlm.nih.gov/pubmed/28953239 http://dx.doi.org/10.3390/cancers9100131 |
Ejemplares similares
-
Polo-like kinase 1 induces epithelial-to-mesenchymal transition and promotes epithelial cell motility by activating CRAF/ERK signaling
por: Wu, Jianguo, et al.
Publicado: (2016) -
Roles of Polo-like kinase 3 in suppressing tumor angiogenesis
por: Xu, Dazhong, et al.
Publicado: (2012) -
Polo-like kinase 4 mediates epithelial–mesenchymal transition in neuroblastoma via PI3K/Akt signaling pathway
por: Tian, Xiangdong, et al.
Publicado: (2018) -
Potential Tumor Suppressor Role of Polo-like Kinase 5 in Cancer
por: Su, Shengqin, et al.
Publicado: (2023) -
A Role for Polo-Like Kinase 4 in Vascular Fibroblast Cell-Type Transition
por: Li, Jing, et al.
Publicado: (2021)