CD47-CAR-T Cells Effectively Kill Target Cancer Cells and Block Pancreatic Tumor Growth

CD47 is a glycoprotein of the immunoglobulin superfamily that is often overexpressed in different types of hematological and solid cancer tumors and plays important role in blocking phagocytosis, increased tumor survival, metastasis and angiogenesis. In the present report, we designed CAR (chimeric...

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Detalles Bibliográficos
Autores principales: Golubovskaya, Vita, Berahovich, Robert, Zhou, Hua, Xu, Shirley, Harto, Hizkia, Li, Le, Chao, Cheng-Chi, Mao, Mike Ming, Wu, Lijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5664078/
https://www.ncbi.nlm.nih.gov/pubmed/29065481
http://dx.doi.org/10.3390/cancers9100139

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5664078/
https://www.ncbi.nlm.nih.gov/pubmed/29065481
http://dx.doi.org/10.3390/cancers9100139

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