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CD47-CAR-T Cells Effectively Kill Target Cancer Cells and Block Pancreatic Tumor Growth
CD47 is a glycoprotein of the immunoglobulin superfamily that is often overexpressed in different types of hematological and solid cancer tumors and plays important role in blocking phagocytosis, increased tumor survival, metastasis and angiogenesis. In the present report, we designed CAR (chimeric...
Autores principales: | Golubovskaya, Vita, Berahovich, Robert, Zhou, Hua, Xu, Shirley, Harto, Hizkia, Li, Le, Chao, Cheng-Chi, Mao, Mike Ming, Wu, Lijun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5664078/ https://www.ncbi.nlm.nih.gov/pubmed/29065481 http://dx.doi.org/10.3390/cancers9100139 |
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