Development and Characterization of Cholangioids from Normal and Diseased Human Cholangiocytes as an In Vitro Model to Study Primary Sclerosing Cholangitis

Primary sclerosing cholangitis (PSC) is an incurable, fibroinflammatory biliary disease for which there is no effective pharmacotherapy. We recently reported cholangiocyte senescence as an important phenotype in PSC while others showed that portal macrophages accumulate in PSC. Unfortunately, our ab...

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Detalles Bibliográficos
Autores principales: Loarca, Lorena, De Assuncao, Thiago M., Jalan-Sakrikar, Nidhi, Bronk, Steve, Krishan, Anuradha, Huang, Bing, Morton, Leslie, Trussoni, Christy, Bonilla, Lorena Marcano, Krueger, Eugene, O’Hara, Steve, Splinter, Patrick, Shi, Guang, Pisarello, María José Lorenzo, Gores, Gregory J., Huebert, Robert C., LaRusso, Nicholas F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5664217/
https://www.ncbi.nlm.nih.gov/pubmed/28892096
http://dx.doi.org/10.1038/labinvest.2017.63

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