Traumatic brain injury may not increase the risk of Alzheimer disease

Traumatic brain injury (TBI) commonly occurs in civilian and military populations. Some epidemiologic studies previously have associated TBI with an increased risk of Alzheimer disease (AD). Recent clinicopathologic and biomarker studies have failed to confirm the relationship of TBI to the developm...

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Detalles Bibliográficos
Autores principales: Weiner, Michael W., Crane, Paul K., Montine, Thomas J., Bennett, David A., Veitch, Dallas P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2017
Materias:
Views & Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5664292/
https://www.ncbi.nlm.nih.gov/pubmed/28978654
http://dx.doi.org/10.1212/WNL.0000000000004608
Descripción
Sumario:Traumatic brain injury (TBI) commonly occurs in civilian and military populations. Some epidemiologic studies previously have associated TBI with an increased risk of Alzheimer disease (AD). Recent clinicopathologic and biomarker studies have failed to confirm the relationship of TBI to the development of AD dementia or pathologic changes, and suggest that other neurodegenerative processes might be linked to TBI. Additional studies are required to determine the long-term consequences of TBI.

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