Traumatic brain injury may not increase the risk of Alzheimer disease

Traumatic brain injury (TBI) commonly occurs in civilian and military populations. Some epidemiologic studies previously have associated TBI with an increased risk of Alzheimer disease (AD). Recent clinicopathologic and biomarker studies have failed to confirm the relationship of TBI to the developm...

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Autores principales: Weiner, Michael W., Crane, Paul K., Montine, Thomas J., Bennett, David A., Veitch, Dallas P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2017
Materias:
Views & Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5664292/
https://www.ncbi.nlm.nih.gov/pubmed/28978654
http://dx.doi.org/10.1212/WNL.0000000000004608
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author Weiner, Michael W.
Crane, Paul K.
Montine, Thomas J.
Bennett, David A.
Veitch, Dallas P.
author_facet Weiner, Michael W.
Crane, Paul K.
Montine, Thomas J.
Bennett, David A.
Veitch, Dallas P.
author_sort Weiner, Michael W.
collection PubMed
description Traumatic brain injury (TBI) commonly occurs in civilian and military populations. Some epidemiologic studies previously have associated TBI with an increased risk of Alzheimer disease (AD). Recent clinicopathologic and biomarker studies have failed to confirm the relationship of TBI to the development of AD dementia or pathologic changes, and suggest that other neurodegenerative processes might be linked to TBI. Additional studies are required to determine the long-term consequences of TBI.
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spelling pubmed-56642922017-11-03 Traumatic brain injury may not increase the risk of Alzheimer disease Weiner, Michael W. Crane, Paul K. Montine, Thomas J. Bennett, David A. Veitch, Dallas P. Neurology Views & Reviews Traumatic brain injury (TBI) commonly occurs in civilian and military populations. Some epidemiologic studies previously have associated TBI with an increased risk of Alzheimer disease (AD). Recent clinicopathologic and biomarker studies have failed to confirm the relationship of TBI to the development of AD dementia or pathologic changes, and suggest that other neurodegenerative processes might be linked to TBI. Additional studies are required to determine the long-term consequences of TBI. Lippincott Williams & Wilkins 2017-10-31 /pmc/articles/PMC5664292/ /pubmed/28978654 http://dx.doi.org/10.1212/WNL.0000000000004608 Text en Copyright © 2017 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of the American Academy of Neurology. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License 4.0 (CC BY-NC-ND) (https://creativecommons.org/licenses/by-nc-nd/4.0/) , which permits downloading and sharing the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.
spellingShingle Views & Reviews
Weiner, Michael W.
Crane, Paul K.
Montine, Thomas J.
Bennett, David A.
Veitch, Dallas P.
Traumatic brain injury may not increase the risk of Alzheimer disease
title Traumatic brain injury may not increase the risk of Alzheimer disease
title_full Traumatic brain injury may not increase the risk of Alzheimer disease
title_fullStr Traumatic brain injury may not increase the risk of Alzheimer disease
title_full_unstemmed Traumatic brain injury may not increase the risk of Alzheimer disease
title_short Traumatic brain injury may not increase the risk of Alzheimer disease
title_sort traumatic brain injury may not increase the risk of alzheimer disease
topic Views & Reviews
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5664292/
https://www.ncbi.nlm.nih.gov/pubmed/28978654
http://dx.doi.org/10.1212/WNL.0000000000004608
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