HIF1A is a critical downstream mediator for hemophagocytic lymphohistiocytosis

Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening syndrome characterized by overwhelming immune activation. A steroid and chemotherapy-based regimen remains as the first-line of therapy but it has substantial morbidity. Thus, novel, less toxic therapy for HLH is urgently needed. Althoug...

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Detalles Bibliográficos
Autores principales: Huang, Rui, Hayashi, Yoshihiro, Yan, Xiaomei, Bu, Jiachen, Wang, Jieyu, Zhang, Yue, Zhou, Yile, Tang, Yuting, Wu, Lingyun, Xu, Zefeng, Liu, Xin, Wang, Qianfei, Zhou, Jianfeng, Xiao, Zhijian, Bridges, James P., Marsh, Rebecca A., Zhang, Kejian, Jordan, Michael B., Li, Yuhua, Huang, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ferrata Storti Foundation 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5664400/
https://www.ncbi.nlm.nih.gov/pubmed/28860338
http://dx.doi.org/10.3324/haematol.2017.174979

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