SIRT1-dependent modulation of methylation and acetylation of histone H3 on lysine 9 (H3K9) in the zygotic pronuclei improves porcine embryo development

BACKGROUND: The histone code is an established epigenetic regulator of early embryonic development in mammals. The lysine residue K9 of histone H3 (H3K9) is a prime target of SIRT1, a member of NAD(+)-dependent histone deacetylase family of enzymes targeting both histone and non-histone substrates....

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Detalles Bibliográficos
Autores principales: Adamkova, Katerina, Yi, Young-Joo, Petr, Jaroslav, Zalmanova, Tereza, Hoskova, Kristyna, Jelinkova, Pavla, Moravec, Jiri, Kralickova, Milena, Sutovsky, Miriam, Sutovsky, Peter, Nevoral, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5664433/
https://www.ncbi.nlm.nih.gov/pubmed/29118980
http://dx.doi.org/10.1186/s40104-017-0214-0

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