Epigenetic control of epilepsy target genes contributes to a cellular memory of epileptogenesis in cultured rat hippocampal neurons

Hypersynchronous neuronal excitation manifests clinically as seizure (ictogenesis), and may recur spontaneously and repetitively after a variable latency period (epileptogenesis). Despite tremendous research efforts to describe molecular pathways and signatures of epileptogenesis, molecular pathomec...

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Detalles Bibliográficos
Autores principales: Kiese, K., Jablonski, J., Hackenbracht, J., Wrosch, J. K., Groemer, T. W., Kornhuber, J., Blümcke, I., Kobow, K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5664434/
https://www.ncbi.nlm.nih.gov/pubmed/29089052
http://dx.doi.org/10.1186/s40478-017-0485-x

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