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Evidence of evolutionary selection for cotranslational folding

Recent experiments and simulations have demonstrated that proteins can fold on the ribosome. However, the extent and generality of fitness effects resulting from cotranslational folding remain open questions. Here we report a genome-wide analysis that uncovers evidence of evolutionary selection for...

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Detalles Bibliográficos
Autores principales: Jacobs, William M., Shakhnovich, Eugene I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5664504/
https://www.ncbi.nlm.nih.gov/pubmed/29073068
http://dx.doi.org/10.1073/pnas.1705772114

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