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M344 promotes nonamyloidogenic amyloid precursor protein processing while normalizing Alzheimer’s disease genes and improving memory

Alzheimer’s disease (AD) comprises multifactorial ailments for which current therapeutic strategies remain insufficient to broadly address the underlying pathophysiology. Epigenetic gene regulation relies upon multifactorial processes that regulate multiple gene and protein pathways, including those...

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Detalles Bibliográficos
Autores principales:	Volmar, Claude-Henry, Salah-Uddin, Hasib, Janczura, Karolina J., Halley, Paul, Lambert, Guerline, Wodrich, Andrew, Manoah, Sivan, Patel, Nidhi H., Sartor, Gregory C., Mehta, Neil, Miles, Nancy T. H., Desse, Sachi, Dorcius, David, Cameron, Michael D., Brothers, Shaun P., Wahlestedt, Claes
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2017
Materias:	PNAS Plus
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5664514/ https://www.ncbi.nlm.nih.gov/pubmed/29073110 http://dx.doi.org/10.1073/pnas.1707544114

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