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Intragenic DNA methylation and BORIS-mediated cancer-specific splicing contribute to the Warburg effect
Aberrant alternative splicing and epigenetic changes are both associated with various cancers, but epigenetic regulation of alternative splicing in cancer is largely unknown. Here we report that the intragenic DNA methylation-mediated binding of Brother of Regulator of Imprinted Sites (BORIS) at the...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5664520/ https://www.ncbi.nlm.nih.gov/pubmed/29073069 http://dx.doi.org/10.1073/pnas.1708447114 |