Dynein/dynactin is necessary for anterograde transport of Mbp mRNA in oligodendrocytes and for myelination in vivo

Oligodendrocytes in the central nervous system produce myelin, a lipid-rich, multilamellar sheath that surrounds axons and promotes the rapid propagation of action potentials. A critical component of myelin is myelin basic protein (MBP), expression of which requires anterograde mRNA transport follow...

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Detalles Bibliográficos
Autores principales: Herbert, Amy L., Fu, Meng-meng, Drerup, Catherine M., Gray, Ryan S., Harty, Breanne L., Ackerman, Sarah D., O’Reilly-Pol, Thomas, Johnson, Stephen L., Nechiporuk, Alex V., Barres, Ben A., Monk, Kelly R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2017
Materias:
PNAS Plus
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5664533/
https://www.ncbi.nlm.nih.gov/pubmed/29073112
http://dx.doi.org/10.1073/pnas.1711088114

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