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Revisiting atenolol as a low passive permeability marker

BACKGROUND: Atenolol, a hydrophilic beta blocker, has been used as a model drug for studying passive permeability of biological membranes such as the blood–brain barrier (BBB) and the intestinal epithelium. However, the extent of S-atenolol (the active enantiomer) distribution in brain has never bee...

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Detalles Bibliográficos
Autores principales:	Chen, Xiaomei, Slättengren, Tim, de Lange, Elizabeth C. M., Smith, David E., Hammarlund-Udenaes, Margareta
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5664587/ https://www.ncbi.nlm.nih.gov/pubmed/29089037 http://dx.doi.org/10.1186/s12987-017-0078-x

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