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Nicotine Component of Cigarette Smoke Extract (CSE) Decreases the Cytotoxicity of CSE in BEAS-2B Cells Stably Expressing Human Cytochrome P450 2A13

Cytochrome P450 2A13 (CYP2A13), an extrahepatic enzyme mainly expressed in the human respiratory system, has been reported to mediate the metabolism and toxicity of cigarette smoke. We previously found that nicotine inhibited 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) metabolism by CYP2A13...

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Detalles Bibliográficos
Autores principales:	Ji, Minghui, Zhang, Yudong, Li, Na, Wang, Chao, Xia, Rong, Zhang, Zhan, Wang, Shou-Lin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5664722/ https://www.ncbi.nlm.nih.gov/pubmed/29027939 http://dx.doi.org/10.3390/ijerph14101221

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