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Uric acid causes kidney injury through inducing fibroblast expansion, Endothelin-1 expression, and inflammation

BACKGROUND: Uric acid (UA) plays important roles in inducing renal inflammation, intra-renal vasoconstriction and renal damage. Endothelin-1 (ET-1) is a well-known profibrotic factor in the kidney and is associated with fibroblast expansion. We examined the role of hyperuricemia conditions in causin...

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Detalles Bibliográficos
Autores principales:	Romi, Muhammad Mansyur, Arfian, Nur, Tranggono, Untung, Setyaningsih, Wiwit Ananda Wahyu, Sari, Dwi Cahyani Ratna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5664905/ https://www.ncbi.nlm.nih.gov/pubmed/29089036 http://dx.doi.org/10.1186/s12882-017-0736-x

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