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Recent insights into PERK-dependent signaling from the stressed endoplasmic reticulum
The unfolded protein response (UPR) is an evolutionarily conserved stress response to intra- and extracellular conditions that disrupt endoplasmic reticulum (ER) protein-folding capacity. The UPR is engaged by a variety of disease conditions, including most cancers as well as both metabolic and neur...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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F1000Research
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5664976/ https://www.ncbi.nlm.nih.gov/pubmed/29152224 http://dx.doi.org/10.12688/f1000research.12138.1 |