Histone Methyltransferase SETDB1 Promotes the Progression of Colorectal Cancer by Inhibiting the Expression of TP53

SETDB1 is a novel histone methyltransferase associated with the functional tri-methylation of histone H3K9. Although aberrant high expression of SETDB1 was experimentally obversed in a variety of solid tumors, its underlying mechanisms in human carcinogenesis are not well known. In this study, we in...

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Detalles Bibliográficos
Autores principales: Chen, Keli, Zhang, Fengjiao, Ding, Jie, Liang, Yonghao, Zhan, Zetao, Zhan, Yizhi, Chen, Long-hua, Ding, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5665049/
https://www.ncbi.nlm.nih.gov/pubmed/29158805
http://dx.doi.org/10.7150/jca.20482

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